George Meyer is equally interested in "classical" music, in fiddle music, and in what they have in common; these interests inform his composing. His pieces for classical string-playing friends make use of lessons learned from the fiddle side, and vice versa.

He has been commissioned by Chamber Music Northwest, Bravo! Vail, Astral Artists and Katie Hyun, Mike Marshall and Caterina Lichtenberg, the Versoi Ensemble, Midsummer's Music, and the Tribeca New Music Festival. He has performed his own compositions at the 92nd Street Y, Stanford Live in Bing Concert Hall, the Phillips Center at University of Florida, the Newman Center at University of Denver, the Gogue Center at Auburn University, Ingram Hall at Vanderbilt University, the Peace Center in Greenville, SC, and Troy Savings Bank Music Hall in Troy, NY, among many others. Festival appearances performing his own compositions include the Aspen Music Festival, Bravo! Vail, Chamber Music Northwest, the Rome Chamber Music Festival, and the Telluride and RockyGrass Bluegrass Festivals.

He recently announced a new violin-piano duo project, Upstream, with composer-pianist Will Healy; they co-compose their repertoire.